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KMID : 0191120070220050908
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Journal of Korean Medical Science
2007 Volume.22 No. 5 p.908 ~ p.911
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Acute Marchiafava-Bignami Disease with Widespread Callosal and Cortical Lesions
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Kim Min-Jeong
Kim Jong-Kuk
Yoo Bong-Goo
Kim Kwang-Soo
Cho Young-Duk
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Abstract
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Marchiafava-Bignami disease (MBD) is a rare alcohol-related disorder that results in progressive demyelination and necrosis of the corpus callosum. The process may extend to the optic chiasm and tracts, cerebellar peduncle, subcortical resion, neighboring white matter, and rarely, cortical gray matter. We report a case of MBD in which fluid-attenuated inversion recovery and diffusion magnetic resonance imaging studies revealed symmetrical hyperintense lesions in the cerebral cortex in addition to the callosal lesions.
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KEYWORD
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Alcohol-Related Disorders, Cerebral Cortex, Diffusion Magnetic Resonance Imaging
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